About temozolom ide
Alkylating chemotherapy medicine
Used for
- Treats certain brain tumours, including glioblastoma and anaplastic astrocytoma.
Usual adult dose
Often 75 mg/m² once daily with radiotherapy, then 150–200 mg/m² daily for five days every 28 days; regimens vary.
Common side effects
- Nausea and vomiting
- Fatigue and headache
- Low blood counts
- Constipation and reduced appetite
Important warnings
- Can cause serious infections or bleeding through low blood counts.
- Requires blood-count monitoring during treatment.
- May harm an unborn baby; effective contraception is needed.
- Rarely causes severe liver injury; liver tests may be monitored.
Pregnancy
Can cause fetal harm. Avoid during pregnancy unless clearly necessary; contraception is recommended during treatment and afterward as directed.
Breastfeeding
Breastfeeding is not recommended during treatment and for at least one week after the final dose.
Interactions
- Valproic acid may increase temozolomide exposure.
- Other medicines that suppress bone marrow may increase blood-count problems.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.