About teicoplani n
Glycopeptide antibiotic
Used for
- Serious infections caused by susceptible Gram-positive bacteria
- Skin, bone, joint, blood, heart, and respiratory infections
- Treatment of Clostridioides difficile infection by mouth
Usual adult dose
Usually 6–12 mg/kg by injection every 12 hours for 3–5 doses, then once daily; dose varies by infection and kidney function.
Usual dose in children
Newborns: 16 mg/kg once, then 8 mg/kg daily. Children: usually 10 mg/kg every 12 hours for 3 doses, then 6–10 mg/kg daily.
Common side effects
- Rash, itching, fever
- Nausea, vomiting, diarrhoea
- Pain or inflammation at injection site
- Changes in kidney function or blood counts
Important warnings
- Serious allergic reactions can occur, especially with previous glycopeptide allergy.
- Kidney function and blood counts may need monitoring during treatment.
- Dose adjustment may be needed with kidney impairment.
- Intravenous teicoplanin is not suitable for treating C. difficile infection in the bowel.
Pregnancy
Human pregnancy information is limited; use only when a clinician considers it necessary.
Breastfeeding
It is not known whether teicoplanin passes into breast milk; discuss use with a healthcare professional.
Interactions
- Aminoglycosides, colistin, amphotericin B, or ciclosporin may increase kidney or hearing toxicity.
- Other medicines that can damage the kidneys or hearing may increase toxicity risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.