About tazemetostat hydrobromide
EZH2 inhibitor anticancer medicine
Used for
- Treats epithelioid sarcoma in certain adults.
- Treats relapsed or refractory follicular lymphoma in certain adults.
Usual adult dose
800 mg by mouth twice daily for both uses, until progression or unacceptable toxicity.
Common side effects
- Tiredness
- Nausea
- Muscle or bone pain
- Low blood cell counts
Important warnings
- May cause new cancers, including blood cancers.
- Can cause serious infections or low blood counts.
- Avoid live vaccines during treatment.
- Strong or moderate CYP3A inhibitors or inducers can change drug levels.
Pregnancy
May harm an unborn baby. Pregnancy testing and effective contraception are recommended during treatment and for six months afterward.
Breastfeeding
Do not breastfeed during treatment and for one week after the final dose.
Interactions
- Strong or moderate CYP3A inhibitors can raise drug levels.
- Strong or moderate CYP3A inducers can lower drug levels.
- Avoid grapefruit and Seville oranges, which may affect drug levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.