About sultiame
Carbonic anhydrase inhibitor antiseizure medicine
Used for
- Add-on treatment for focal seizures, particularly in children with benign epilepsy with centrotemporal spikes.
Usual adult dose
Usually started at 50–100 mg daily, then increased gradually; specialist-directed dosing varies by seizure type and region.
Usual dose in children
Usually started at 2.5–5 mg/kg daily in divided doses, then increased gradually; specialist-directed.
Common side effects
- Tingling or numbness
- Loss of appetite, nausea, or stomach discomfort
- Dizziness, tiredness, or headache
- Rapid breathing
Important warnings
- Use under specialist supervision; do not stop suddenly.
- May cause metabolic acidosis and kidney stones.
- Seek urgent assessment for severe breathing difficulty, rash, or unusual bruising.
- Use caution with kidney or liver problems.
Pregnancy
Pregnancy data are limited. Seizures and treatment risks require specialist review; do not stop treatment abruptly.
Breastfeeding
Information is limited; discuss potential infant exposure and monitoring with a clinician.
Interactions
- Other carbonic anhydrase inhibitors may increase acidosis or kidney-stone risk.
- Phenytoin levels may rise; monitoring may be needed.
- Alcohol and sedating medicines may worsen drowsiness or dizziness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.