About sulpiride
Atypical antipsychotic (benzamide)
Used for
- Schizophrenia and other psychotic disorders
- In some countries, short-term treatment of certain anxiety or depressive symptoms
Usual adult dose
For schizophrenia, commonly 400–800 mg daily in divided doses; dosing varies by symptoms and local guidance.
Common side effects
- Sleepiness or dizziness
- Raised prolactin, causing breast changes or menstrual problems
- Movement problems, including tremor or stiffness
- Weight gain or constipation
Important warnings
- May cause serious heart-rhythm problems, especially with risk factors or interacting medicines
- Can cause movement disorders and raised prolactin
- Use caution with kidney problems; dose reduction may be needed
- Do not stop suddenly without medical guidance
Pregnancy
Use only when clearly needed; late-pregnancy exposure may cause withdrawal or movement symptoms in newborns.
Breastfeeding
Sulpiride enters breast milk and may affect the infant; specialist advice is needed.
Interactions
- Medicines that affect heart rhythm, including some antibiotics and antipsychotics
- Levodopa and dopamine agonists
- Medicines that cause sleepiness, including alcohol and sedatives
- Antacids or sucralfate can reduce absorption; separate dosing
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.