About sugammadex sodium
Selective neuromuscular blocker reversal agent
Used for
- Reverses rocuronium- or vecuronium-induced muscle relaxation after surgery.
Usual adult dose
Given intravenously once: 2 mg/kg for moderate block, 4 mg/kg for deep block, or 16 mg/kg for immediate reversal.
Usual dose in children
For children aged 2 years and older: 2 mg/kg intravenously for moderate rocuronium-induced block; other uses are not well established.
Common side effects
- Nausea
- Vomiting
- Pain
- Low blood pressure
Important warnings
- Must be given where breathing and heart function can be monitored.
- May cause severe allergic reactions or marked slowing of the heart rate.
- Muscle weakness can return; monitoring is needed until recovery is sustained.
- Can reduce the effectiveness of hormonal contraceptives for seven days.
Pregnancy
Human pregnancy data are limited; use only when clinically necessary.
Breastfeeding
It is unknown whether sugammadex enters breast milk; effects on a nursing infant are unclear.
Interactions
- May reduce hormonal contraceptive effectiveness; use additional nonhormonal contraception for seven days.
- May bind certain medicines, including toremifene and fusidic acid, potentially affecting their effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.