About sterile ceftizoxim e sodium
Third-generation cephalosporin antibiotic
Used for
- Treats susceptible bacterial infections, including serious respiratory, urinary, abdominal, skin, bone, and joint infections.
- May be used for certain pelvic infections or gonorrhea when prescribed.
Usual adult dose
Usually 1–2 g intravenously every 8–12 hours; severe infections may require higher doses. Adjust for kidney impairment.
Usual dose in children
Usually 50–100 mg/kg/day intravenously, divided every 6–8 hours; maximum depends on infection and clinical guidance.
Common side effects
- Diarrhea, nausea, or vomiting
- Rash or other allergic reactions
- Pain or inflammation at injection site
- Changes in blood counts or liver tests
Important warnings
- Serious allergic reactions can occur, especially with cephalosporin or penicillin allergy.
- Antibiotic-associated severe diarrhea can occur during or after treatment.
- Dose adjustment may be needed with impaired kidney function.
- Use only for bacterial infections; unnecessary use promotes antibiotic resistance.
Pregnancy
Human pregnancy data are limited. Use when clearly needed and prescribed by a clinician.
Breastfeeding
Small amounts may enter breast milk; monitor the infant for diarrhea, thrush, or rash.
Interactions
- Probenecid may increase ceftizoxime levels.
- Other medicines that can affect kidney function may increase kidney-related risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.