About spironolactone
Potassium-sparing diuretic; aldosterone blocker
Used for
- Heart failure and high blood pressure
- Fluid buildup from liver disease or kidney problems
- High aldosterone levels
- Certain cases of acne or excess hair growth
Usual adult dose
Usually 25–100 mg daily for heart failure; other conditions often require different doses.
Usual dose in children
Dose is based on weight and condition; specialist-directed dosing is typical.
Common side effects
- High potassium
- Dizziness or low blood pressure
- Breast tenderness or enlargement
- Menstrual changes
Important warnings
- Can cause dangerously high potassium, especially with kidney problems.
- Blood potassium and kidney function need monitoring.
- May cause dehydration or worsen kidney function.
- Avoid potassium supplements and salt substitutes unless prescribed.
Pregnancy
May affect fetal sex development; generally avoided during pregnancy unless a clinician determines benefits outweigh risks.
Breastfeeding
Small amounts enter breast milk; generally considered compatible, but discuss use with a healthcare professional.
Interactions
- ACE inhibitors or ARBs may increase potassium.
- Potassium supplements and potassium-based salt substitutes raise potassium.
- NSAIDs may worsen kidney function or reduce its effect.
- Lithium levels may rise.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.