About sotagliflozin
SGLT1/SGLT2 inhibitor
Used for
- Reduces cardiovascular death, heart-failure hospitalizations, and urgent heart-failure visits in adults with heart failure.
- Reduces cardiovascular death and worsening heart failure in adults with type 2 diabetes, chronic kidney disease, and cardiovascular risk.
Usual adult dose
Start 200 mg once daily before the first meal; increase to 400 mg once daily if tolerated, according to prescribing information.
Common side effects
- Diarrhea
- Genital yeast infections
- Urinary tract infections
- Dehydration or low blood pressure
Important warnings
- May cause diabetic ketoacidosis, sometimes with near-normal blood sugar.
- Risk of dehydration, low blood pressure, and kidney-function changes; monitor as appropriate.
- Rarely causes serious genital or urinary infections.
- Not recommended with severe kidney impairment or dialysis.
Pregnancy
May harm the fetus, especially during the second and third trimesters; avoid use during pregnancy.
Breastfeeding
Breastfeeding is not recommended during treatment because of potential harm to a nursing infant.
Interactions
- Insulin or sulfonylureas may increase low-blood-sugar risk.
- Diuretics may increase dehydration and low-blood-pressure risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.