About sorafenib tosylate
Multikinase inhibitor anticancer medicine
Used for
- Treats advanced kidney cancer
- Treats unresectable liver cancer
- Treats radioactive iodine-resistant thyroid cancer
Usual adult dose
Usually 400 mg by mouth twice daily; specialists may adjust the dose.
Common side effects
- Diarrhea
- Hand-foot skin reaction
- Rash
- High blood pressure
Important warnings
- Can cause serious bleeding, heart problems, or liver injury.
- May impair wound healing; it is usually stopped before surgery.
- Can harm an unborn baby; effective contraception is needed during treatment.
- Monitor blood pressure and liver tests during treatment.
Pregnancy
Can cause fetal harm. Avoid during pregnancy; use effective contraception during treatment and for at least 6 months after the last dose.
Breastfeeding
Do not breastfeed during treatment and for at least 2 weeks after the last dose.
Interactions
- Warfarin and other blood thinners may increase bleeding risk.
- Strong CYP3A4 inducers, such as rifampin, may reduce sorafenib levels.
- Some medicines that affect liver enzymes can alter sorafenib exposure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.