About somatropin recombinant
Recombinant human growth hormone
Used for
- Growth hormone deficiency in children and adults
- Growth failure in children with Turner syndrome, Prader-Willi syndrome, or chronic kidney disease
- Short stature in children born small for gestational age without catch-up growth
Usual adult dose
Individualized; commonly starts at 0.15–0.3 mg daily for adult growth hormone deficiency, adjusted using clinical response and blood tests.
Usual dose in children
Individualized by weight or body surface area; commonly 0.16–0.24 mg/kg weekly, divided into daily injections, depending on condition.
Common side effects
- Injection-site reactions
- Joint or muscle pain
- Swelling or fluid retention
- Headache
Important warnings
- May reduce insulin sensitivity and raise blood sugar.
- Intracranial hypertension can occur, especially early in treatment.
- Avoid with active cancer or acute critical illness after major surgery or trauma.
- Prader-Willi syndrome carries a risk of serious breathing problems; assess risk factors.
Pregnancy
Limited human data; use during pregnancy only when clearly needed and prescribed.
Breastfeeding
Effects on a nursing infant are uncertain; use only under medical supervision.
Interactions
- Corticosteroids may reduce growth-promoting effects.
- May alter insulin or other diabetes medicine requirements.
- Oral estrogen may reduce response.
- Thyroid replacement needs may change during treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.