About somatropin
Recombinant human growth hormone
Used for
- Growth hormone deficiency in children and adults
- Growth failure in children with certain syndromes or chronic kidney disease
- Short stature in children born small for gestational age without catch-up growth
Usual adult dose
For adult growth hormone deficiency, usually start at 0.15–0.3 mg under the skin daily; adjust gradually using clinical response and blood tests.
Usual dose in children
Usually 0.16–0.24 mg/kg per week under the skin, divided into daily doses; dose depends on the condition.
Common side effects
- Injection-site reactions or pain
- Joint or muscle pain
- Swelling from fluid retention
- Headache
Important warnings
- May reduce insulin sensitivity and raise blood sugar.
- Can cause raised pressure around the brain; severe headache or vision changes need assessment.
- Do not use with active cancer or acute critical illness.
- Growth plates must remain open for treatment of short stature.
Pregnancy
Human pregnancy data are limited; use only when the prescriber considers it necessary.
Breastfeeding
It is unknown whether somatropin passes into breast milk; seek advice from a healthcare professional.
Interactions
- May affect insulin or other diabetes medicines.
- Oral estrogen can alter dose requirements.
- Corticosteroids may reduce growth-promoting effects.
- Thyroid replacement needs may change during treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.