About solriamfetol
Dopamine and norepinephrine reuptake inhibitor
Used for
- Improves excessive daytime sleepiness in adults with narcolepsy.
- Improves excessive daytime sleepiness in adults with obstructive sleep apnea.
Usual adult dose
Narcolepsy: 75 mg once each morning, increased if needed to 150 mg. Obstructive sleep apnea: 37.5 mg once each morning, increased if needed to 150 mg.
Common side effects
- Headache
- Nausea
- Decreased appetite
- Anxiety or insomnia
Important warnings
- Can raise blood pressure and heart rate; monitor these during treatment.
- Avoid within nine hours of bedtime because it may disrupt sleep.
- Not a treatment for airway obstruction in obstructive sleep apnea.
- Avoid with monoamine oxidase inhibitors or within 14 days of their use.
Pregnancy
Human pregnancy information is limited; use requires weighing potential benefits against possible risks.
Breastfeeding
It is unknown whether solriamfetol passes into human milk; effects on infants are uncertain.
Interactions
- Monoamine oxidase inhibitors can cause dangerous blood pressure increases.
- Other medicines that raise blood pressure or heart rate may increase cardiovascular risks.
- Dopaminergic medicines may increase effects such as restlessness or insomnia.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.