About sodium stibogluc onate
Pentavalent antimonial antiparasitic
Used for
- Treatment of visceral, cutaneous, and mucosal leishmaniasis
Usual adult dose
Usually 20 mg antimony/kg injected daily for 20–28 days; specialist-directed dosing varies by disease.
Usual dose in children
Usually 20 mg antimony/kg injected daily for 20–28 days; specialist-directed dosing varies by disease.
Common side effects
- Nausea, vomiting, abdominal pain, or diarrhea
- Muscle or joint pain, headache, or fatigue
- Injection-site pain
- Raised pancreatic enzymes or liver tests
Important warnings
- Requires specialist supervision and monitoring, including heart tracing and blood tests.
- Can cause serious heart rhythm changes, pancreatitis, liver injury, or kidney problems.
- Avoid or use particular caution with heart, liver, or kidney disease.
- Treatment choice depends on parasite location and local resistance.
Pregnancy
Safety is not well established; use only when specialist assessment concludes benefits outweigh risks.
Breastfeeding
Safety is not well established; specialist advice is needed before use.
Interactions
- Medicines that affect heart rhythm may increase risk of dangerous rhythm changes.
- Other medicines toxic to the heart, liver, pancreas, or kidneys may increase harm.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.