About sodium oxybate
Central nervous system depressant
Used for
- Treats excessive daytime sleepiness and cataplexy in narcolepsy.
Usual adult dose
Narcolepsy: usually 4.5 g nightly, divided into two doses; may be increased gradually to 6–9 g nightly.
Usual dose in children
Narcolepsy in children aged 7 years and older: dose is weight-based, divided into two nightly doses, and gradually adjusted.
Common side effects
- Nausea or vomiting
- Dizziness
- Headache
- Bedwetting
Important warnings
- Can cause profound sleepiness, slowed breathing, coma, or death.
- Avoid alcohol and sedative medicines, including opioids and benzodiazepines.
- Use only through the restricted safety program; secure it against misuse.
- May cause depression, confusion, or suicidal thoughts.
Pregnancy
Human pregnancy information is limited; use only when the expected benefit outweighs potential risk.
Breastfeeding
It is unknown whether sodium oxybate enters breast milk; effects on a nursing infant are uncertain.
Interactions
- Alcohol and sedatives can dangerously increase breathing suppression and sedation.
- Divalproex increases sodium oxybate exposure; a lower sodium oxybate dose may be needed.
- Other medicines that depress the central nervous system may increase serious adverse effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.