About sodium fusidate
Fusidic acid antibiotic
Used for
- Serious staphylococcal infections, often alongside another antibiotic.
- Bone and joint infections caused by susceptible staphylococci.
Usual adult dose
Commonly 500 mg to 1 g intravenously every 8 hours; dosing varies by infection and local guidance.
Usual dose in children
Specialist-directed dosing based on body weight and infection; intravenous use is uncommon in children.
Common side effects
- Nausea, vomiting, or abdominal discomfort.
- Raised liver enzymes or jaundice.
- Pain or inflammation at the injection site.
- Rash or allergic reaction.
Important warnings
- Use with another suitable antibiotic to reduce resistance.
- Monitor liver function during treatment.
- Intravenous administration requires careful preparation and monitoring.
- Avoid in severe liver disease unless specialist-directed.
Pregnancy
Safety information is limited; use only when a clinician considers treatment necessary.
Breastfeeding
Small amounts may enter breast milk; clinical advice is needed, especially with prolonged treatment.
Interactions
- Statins: increased risk of severe muscle injury; usually avoid together.
- Warfarin: anticoagulant effect may change; monitor closely.
- HIV medicines such as ritonavir or saquinavir: serious interactions; avoid combination.
- Ciclosporin: blood levels may rise; monitoring may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.