About sitagliptin
DPP-4 inhibitor antidiabetic
Used for
- Improves blood sugar control in adults with type 2 diabetes, alongside diet and exercise.
- May be used alone or with other diabetes medicines.
Usual adult dose
Usually 100 mg by mouth once daily; reduce for impaired kidney function.
Common side effects
- Headache
- Upper respiratory symptoms
- Low blood sugar, especially with insulin or sulfonylureas
- Joint pain or stomach upset
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Dose adjustment is needed with reduced kidney function.
- Rarely, can cause pancreatitis, severe allergic reactions, or heart failure.
- Seek urgent assessment for severe, persistent abdominal pain or facial swelling.
Pregnancy
Human pregnancy information is limited; use only if a clinician considers it necessary.
Breastfeeding
Unknown whether it passes into human milk; discuss use with a healthcare professional.
Interactions
- Insulin or sulfonylureas can increase low blood sugar risk.
- Digoxin levels may rise slightly; monitoring may be considered.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.