About sitagliptin as hcl
DPP-4 inhibitor for type 2 diabetes
Used for
- Helps control blood sugar in adults with type 2 diabetes, alongside diet and exercise.
- May be used alone or with other diabetes medicines.
Usual adult dose
Usually 100 mg once daily; lower doses are used with reduced kidney function.
Common side effects
- Headache
- Stuffy or runny nose and sore throat
- Low blood sugar, especially with insulin or sulfonylureas
- Stomach discomfort or diarrhea
Important warnings
- Rarely, can cause severe, persistent abdominal pain from pancreatitis.
- Seek urgent care for facial or throat swelling, or trouble breathing.
- Kidney function should be checked; dose may need adjustment.
- Stop and seek medical care for severe joint pain or blistering skin rash.
Pregnancy
Human pregnancy information is limited; use only if a clinician considers it necessary.
Breastfeeding
It is not known whether sitagliptin passes into human milk; discuss use with a clinician.
Interactions
- Insulin or sulfonylureas increase low-blood-sugar risk; their doses may need adjustment.
- Digoxin levels can rise slightly; monitoring may be considered.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.