About sitagliptin hydrochloride
Dipeptidyl peptidase-4 (DPP-4) inhibitor
Used for
- Improves blood sugar control in adults with type 2 diabetes, alongside diet and exercise.
Usual adult dose
Usually 100 mg once daily; lower doses are used with reduced kidney function.
Common side effects
- Headache
- Upper respiratory symptoms
- Low blood sugar, especially with insulin or sulfonylureas
- Joint pain
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Rarely causes pancreatitis or severe allergic reactions.
- Kidney function should guide dosing.
- Seek prompt medical assessment for severe, persistent abdominal pain.
Pregnancy
Limited information is available; use during pregnancy requires clinician assessment of benefits and risks.
Breastfeeding
It is not known whether sitagliptin passes into human milk; discuss use with a clinician.
Interactions
- Insulin or sulfonylureas can increase low-blood-sugar risk.
- Digoxin levels may rise slightly; monitoring may be considered.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.