About silver sulfadiazine
Topical sulfonamide antimicrobial
Used for
- Prevention and treatment of infection in serious burns.
Usual adult dose
Apply a thin layer to affected burn areas once or twice daily, following wound-care instructions.
Usual dose in children
For children over 2 months, apply once or twice daily to burn areas; dosing and suitability require clinician guidance.
Common side effects
- Burning, itching, rash, or pain at the application site.
- Rarely, low white blood cell counts or severe allergic reactions.
Important warnings
- Not for use in premature infants or newborns younger than 2 months.
- Avoid near the end of pregnancy because sulfonamides may harm the newborn.
- Use caution with sulfonamide allergy, kidney or liver problems, or glucose-6-phosphate dehydrogenase deficiency.
- May delay wound healing or cause skin discoloration.
Pregnancy
Avoid near term; use earlier in pregnancy only when clearly needed under medical supervision.
Breastfeeding
Use with caution; avoid applying to areas that could contact an infant’s skin or mouth.
Interactions
- May increase effects of blood-thinning medicines such as warfarin.
- Cimetidine may increase the risk of low white blood cell counts.
- Enzymatic wound-cleansing products may be inactivated.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.