About sevelamer hydrochloride
Phosphate-binding medicine
Used for
- Lowers high blood phosphate in people receiving dialysis for chronic kidney disease
Usual adult dose
Usually 800–1,600 mg with each meal; dose is adjusted to blood phosphate levels.
Common side effects
- Nausea or vomiting
- Diarrhea or constipation
- Stomach pain, gas, or indigestion
Important warnings
- Take with meals; swallow tablets whole.
- May cause bowel blockage or serious constipation, especially with bowel disorders.
- Can reduce absorption of other medicines; separate doses as directed.
- Use caution with difficulty swallowing or a history of intestinal blockage.
Pregnancy
Limited information; use only when the expected benefit outweighs potential risks.
Breastfeeding
It is not absorbed into the bloodstream, so exposure through breast milk is unlikely; discuss use with a clinician.
Interactions
- May reduce absorption of levothyroxine, ciprofloxacin, mycophenolate, and some seizure medicines.
- Separate interacting medicines from sevelamer as directed; monitor relevant drug levels or treatment response.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.