About sertindole
Atypical antipsychotic
Used for
- Treatment of schizophrenia in adults when other antipsychotics have not worked or were not tolerated.
Usual adult dose
Usually started at 4 mg once daily, increased gradually to 12–20 mg once daily; maximum 24 mg daily.
Common side effects
- Dizziness or fainting
- Nasal congestion
- Weight gain
- Prolonged QT interval and abnormal heart rhythms
Important warnings
- Can prolong the QT interval, potentially causing life-threatening heart rhythms.
- Heart tracing and blood tests are generally needed before and during treatment.
- May cause low blood pressure, especially when starting or increasing the dose.
- Do not stop suddenly without medical supervision.
Pregnancy
Use during pregnancy only when clearly necessary; late-pregnancy exposure may cause newborn withdrawal or movement symptoms.
Breastfeeding
Breastfeeding is generally not recommended during treatment because effects on the infant are uncertain.
Interactions
- Avoid medicines that prolong the QT interval, including some antibiotics and antiarrhythmics.
- Some medicines increase sertindole levels, including fluoxetine and fluvoxamine.
- Carbamazepine, phenytoin, and rifampicin can lower sertindole levels.
- Alcohol and medicines causing drowsiness may worsen impairment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.