About saxagliptin
Dipeptidyl peptidase-4 (DPP-4) inhibitor
Used for
- Helps control blood sugar in adults with type 2 diabetes, alongside diet and exercise.
Usual adult dose
Usually 2.5 or 5 mg by mouth once daily; dose may be reduced for kidney problems or certain interacting medicines.
Common side effects
- Upper respiratory tract infections
- Headache
- Urinary tract infections
- Low blood sugar, especially with insulin or sulfonylureas
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Seek urgent care for severe, persistent abdominal pain; pancreatitis has been reported.
- Heart failure has been reported; risk may be higher with existing heart or kidney disease.
- Rarely, severe joint pain or serious allergic reactions can occur.
Pregnancy
Human pregnancy information is limited; use only when a clinician determines it is needed.
Breastfeeding
It is not known whether saxagliptin passes into breast milk; discuss use with a healthcare professional.
Interactions
- Strong CYP3A4/5 inhibitors, such as ketoconazole, can increase saxagliptin levels.
- Insulin or sulfonylureas increase low-blood-sugar risk; their doses may need adjustment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.