About sargramostim
Granulocyte-macrophage colony-stimulating factor
Used for
- Helps restore white blood cells after certain cancer treatments or bone marrow transplantation.
- Supports bone marrow recovery after acute myeloid leukemia chemotherapy.
- Treats poor blood-cell production after bone marrow transplantation or in certain marrow disorders.
Usual adult dose
Varies by indication; commonly 250 mcg/m² daily by injection, with duration and timing determined by the treatment protocol.
Usual dose in children
Specialist-determined; commonly 250 mcg/m² daily for selected indications.
Common side effects
- Fever, chills, fatigue, or headache
- Bone, muscle, or joint pain
- Nausea, vomiting, or diarrhea
- Injection-site reactions or swelling
Important warnings
- Can cause serious allergic reactions, including anaphylaxis.
- May cause fluid retention, breathing problems, or capillary leak syndrome.
- May worsen abnormal white blood cell growth in some blood cancers.
- Dose and timing depend on the indication and blood-count monitoring.
Pregnancy
Human pregnancy data are limited; use only when a clinician judges potential benefits outweigh risks.
Breastfeeding
It is unknown whether sargramostim passes into breast milk; discuss breastfeeding with the treating clinician.
Interactions
- Lithium or other medicines that stimulate white blood cell production may increase blood-cell responses.
- Chemotherapy and radiation timing can affect treatment safety and effectiveness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.