About rosuvastatin calcium + ezetimibe
Statin and cholesterol absorption inhibitor
Used for
- Lowers LDL (“bad”) cholesterol and other blood fats
- Reduces cardiovascular risk in some people with high cholesterol
Usual adult dose
Usually one tablet once daily; dose is chosen according to cholesterol levels and treatment response.
Usual dose in children
For inherited high cholesterol, ages 6 and older: rosuvastatin 5–10 mg plus ezetimibe 10 mg once daily, under specialist supervision.
Common side effects
- Muscle aches or weakness
- Headache
- Nausea or abdominal discomfort
- Raised liver enzymes
Important warnings
- Seek urgent care for severe muscle pain, weakness, or dark urine.
- Liver disease may make treatment unsuitable; liver tests may be needed.
- Avoid during pregnancy; stop and contact a clinician if pregnancy occurs.
- Not generally recommended while breastfeeding.
Pregnancy
Avoid during pregnancy. Cholesterol treatment is usually stopped during pregnancy; seek clinician guidance if pregnant or planning pregnancy.
Breastfeeding
Not generally recommended because both medicines may pose risks to a nursing infant; discuss alternatives with a clinician.
Interactions
- Cyclosporine can greatly increase rosuvastatin exposure.
- Warfarin may require closer blood-clotting monitoring.
- Some antiviral medicines and fibrates increase muscle-related risks.
- Bile-acid sequestrants can reduce ezetimibe absorption; separate doses.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.