About romiplostim micrograms
Thrombopoietin receptor agonist
Used for
- Treats low platelet counts in chronic immune thrombocytopenia (ITP) when other treatments are insufficient.
- May be used in children aged 1 year or older with ITP lasting at least six months.
Usual adult dose
Injected under the skin once weekly; start at 1 microgram/kg and adjust to maintain platelets at or above 50 × 10⁹/L, up to 10 micrograms/kg weekly.
Usual dose in children
For children aged 1 year or older: injected under the skin once weekly, starting at 1 microgram/kg; adjust according to platelet counts, up to 10 micrograms/kg weekly.
Common side effects
- Headache
- Joint or muscle pain
- Dizziness
- Blood clots or increased bone marrow reticulin
Important warnings
- Platelet counts can become too high, increasing clot risk; regular blood tests are needed.
- Platelets may fall after stopping treatment, sometimes causing serious bleeding.
- Not for low platelet counts caused by conditions other than ITP unless specifically indicated.
- Use caution with liver disease or a history of blood clots.
Pregnancy
Human pregnancy information is limited; use only when the expected benefit outweighs potential risks.
Breastfeeding
It is unknown whether romiplostim passes into human milk; discuss the benefits and risks of treatment and breastfeeding.
Interactions
- No specific clinically important drug interactions are established.
- Medicines affecting platelet function or clotting may influence bleeding or clot risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.