About roflumilas t
Phosphodiesterase-4 inhibitor
Used for
- Long-term treatment of severe COPD with chronic bronchitis and frequent exacerbations; used alongside inhaled medicines.
Usual adult dose
One tablet by mouth once daily.
Common side effects
- Diarrhea, nausea, reduced appetite
- Weight loss
- Headache, dizziness, insomnia
- Mood changes
Important warnings
- Not for sudden breathing attacks or asthma.
- Use cautiously with depression or suicidal thoughts.
- Monitor weight; substantial unexplained loss needs medical review.
- Avoid in moderate or severe liver impairment.
Pregnancy
Generally avoid during pregnancy; human safety information is limited.
Breastfeeding
Breastfeeding safety is uncertain; use requires clinical assessment.
Interactions
- Strong CYP3A4 inhibitors, such as ketoconazole, may increase roflumilast exposure.
- Rifampicin and other strong enzyme inducers may reduce effectiveness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.