About rocuronium bromide
Nondepolarizing neuromuscular blocker
Used for
- Relaxes muscles during general anaesthesia to support surgery.
- Helps facilitate placement of a breathing tube.
- Supports controlled ventilation in selected critically ill patients.
Usual adult dose
Given intravenously by trained clinicians; doses vary by procedure and anaesthetic plan. Common intubation dose: 0.6 mg/kg.
Usual dose in children
Given intravenously by trained clinicians; dosing is weight-based and varies by age and procedure.
Common side effects
- Prolonged muscle weakness or paralysis
- Low blood pressure
- Fast heart rate
- Allergic reactions, rarely severe
Important warnings
- Causes paralysis, including of breathing muscles; ventilation and monitoring are essential.
- Must be administered by trained clinicians with airway and resuscitation equipment available.
- Effect may last longer with liver or kidney problems, older age, or interacting medicines.
- Does not cause unconsciousness or relieve pain; anaesthesia is also required.
Pregnancy
Use only when clinically necessary; evidence is limited, and the anaesthesia team weighs potential risks and benefits.
Breastfeeding
A single dose is unlikely to affect a nursing infant because little is expected to enter milk; seek clinical guidance for repeated use.
Interactions
- Anaesthetics and magnesium may intensify or prolong muscle relaxation.
- Certain antibiotics, including aminoglycosides, may intensify paralysis.
- Some anticonvulsants may reduce or alter its effect.
- Other neuromuscular blockers can change the strength or duration of its effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.