About rivarozaba n
Direct oral factor Xa inhibitor
Used for
- Prevention of stroke and systemic embolism in nonvalvular atrial fibrillation
- Treatment of deep vein thrombosis and pulmonary embolism
- Prevention of recurrent deep vein thrombosis or pulmonary embolism
- Prevention of venous clots after hip or knee replacement surgery
Usual adult dose
Atrial fibrillation: 20 mg once daily with food. DVT/PE: 15 mg twice daily for 21 days, then 20 mg once daily with food. Doses vary by kidney function and indication.
Usual dose in children
For children with blood clots, weight-based doses are used after initial injectable anticoagulation; specialist dosing is required.
Common side effects
- Bleeding or bruising
- Anemia
- Nausea
- Stomach or back pain
Important warnings
- Can cause serious or fatal bleeding
- Do not stop suddenly without medical direction; clot risk may increase
- Avoid with active bleeding or certain artificial heart valves
- Dose may need adjustment or avoidance with kidney or liver problems
Pregnancy
May cause harm or bleeding during pregnancy; use requires specialist assessment.
Breastfeeding
Avoid during breastfeeding because safety is uncertain; discuss alternatives with a clinician.
Interactions
- Other blood thinners and antiplatelet medicines increase bleeding risk
- NSAIDs such as ibuprofen increase bleeding risk
- Some antifungals and HIV medicines can raise levels
- Rifampin, carbamazepine, phenytoin, and St John’s wort can reduce effect
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.