About rivaroxaban in house
Direct factor Xa inhibitor anticoagulant
Used for
- Preventing blood clots after hip or knee replacement surgery
- Preventing stroke and blood clots in nonvalvular atrial fibrillation
- Treating deep vein thrombosis and pulmonary embolism
- Reducing recurrence of deep vein thrombosis or pulmonary embolism
Usual adult dose
Dose depends on use: commonly 10 mg once daily after hip or knee replacement; other uses require different doses.
Usual dose in children
For children, weight-based doses are used for treating or preventing blood clots; dosing is specialist-directed.
Common side effects
- Bleeding, including serious or internal bleeding
- Easy bruising
- Nausea
- Anemia
Important warnings
- Seek urgent care for serious bleeding or signs of bleeding in the brain.
- Stopping suddenly can increase blood clot or stroke risk.
- Spinal or epidural procedures can cause a rare spinal blood clot and paralysis.
- Kidney or liver problems may increase bleeding risk.
Pregnancy
May cause harm or bleeding during pregnancy; generally avoided unless a specialist determines it is necessary.
Breastfeeding
Unknown whether it passes into breast milk; use during breastfeeding requires medical guidance.
Interactions
- Other anticoagulants and antiplatelet medicines increase bleeding risk.
- NSAIDs such as ibuprofen can increase bleeding risk.
- Some antifungals and HIV medicines can raise rivaroxaban levels.
- Rifampin, carbamazepine, and St John’s wort can reduce its effect.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.