About rivaroxaba n
Direct oral factor Xa anticoagulant
Used for
- Prevention of stroke and systemic embolism in non-valvular atrial fibrillation
- Treatment of deep vein thrombosis and pulmonary embolism
- Prevention of recurrent deep vein thrombosis and pulmonary embolism
- Prevention of blood clots after certain hip or knee replacements
Usual adult dose
Atrial fibrillation: 20 mg once daily with food. DVT or pulmonary embolism: 15 mg twice daily for 21 days, then 20 mg once daily with food.
Usual dose in children
For children with venous clots, dosing depends on age, weight, and treatment stage; specialist prescribing is required.
Common side effects
- Bleeding or easy bruising
- Anemia
- Nausea
- Abdominal pain
Important warnings
- Serious or fatal bleeding can occur.
- Do not stop suddenly without medical direction; clot risk may increase.
- Kidney or liver disease can affect safety and dosing.
- Spinal or epidural procedures can cause serious bleeding complications.
Pregnancy
Generally avoided; it may cause bleeding and harm the fetus. Use during pregnancy requires specialist assessment.
Breastfeeding
Not recommended because it may pass into breast milk; alternative treatment is generally preferred.
Interactions
- Other anticoagulants or antiplatelet medicines increase bleeding risk.
- NSAIDs such as ibuprofen can increase bleeding risk.
- Strong P-glycoprotein and CYP3A inhibitors or inducers can alter rivaroxaban levels.
- St John’s wort may reduce its effect.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.