About rivaroaba n
Direct oral anticoagulant (factor Xa inhibitor)
Used for
- Prevention of blood clots after hip or knee replacement surgery
- Treatment and prevention of deep vein thrombosis and pulmonary embolism
- Stroke prevention in adults with nonvalvular atrial fibrillation
Usual adult dose
Common doses vary by use: 10 mg once daily after joint replacement; 15 mg twice daily initially for clots, then 20 mg daily; 20 mg daily for atrial fibrillation.
Usual dose in children
For certain children with blood clots, dosing is weight-based and specialist-directed; this tablet may not be suitable.
Common side effects
- Bleeding or bruising
- Nausea
- Anemia
- Dizziness
Important warnings
- Can cause serious or fatal bleeding.
- Do not stop suddenly without medical direction; clot risk may rise.
- Avoid in active major bleeding; caution with kidney or liver disease.
- Spinal or epidural procedures can increase risk of serious bleeding.
Pregnancy
Generally avoided during pregnancy because of bleeding risk; specialist advice is needed.
Breastfeeding
Use is generally not recommended while breastfeeding; discuss alternatives with a clinician.
Interactions
- Other anticoagulants and antiplatelet medicines increase bleeding risk.
- NSAIDs such as ibuprofen can increase bleeding.
- Some antifungals and HIV medicines raise rivaroxaban levels.
- Rifampin, carbamazepine, and St John’s wort can reduce its effect.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.