About ritonavir
HIV protease inhibitor and booster
Used for
- Boosts blood levels of other HIV medicines
- Used with other medicines to treat HIV infection
Usual adult dose
As a booster, commonly 100–200 mg once or twice daily with another HIV medicine; dose varies by regimen.
Usual dose in children
Used with other HIV medicines; dose is based on body size and the specific regimen.
Common side effects
- Nausea, vomiting, diarrhea, or abdominal pain
- Altered taste
- Raised cholesterol or triglycerides
- Liver enzyme changes
Important warnings
- Many serious interactions; full medication review is important.
- Can cause liver problems, especially with existing liver disease.
- May raise blood sugar or worsen diabetes.
- Do not stop or change HIV treatment without medical guidance.
Pregnancy
Ritonavir is used in pregnancy as an HIV treatment booster when prescribed; regimen choice requires specialist review.
Breastfeeding
HIV guidance generally advises against breastfeeding where safe alternatives are available, because HIV can pass through breast milk.
Interactions
- Strong interactions with many medicines, including some sedatives and heart-rhythm drugs.
- Can reduce effectiveness of hormonal contraceptives; additional or alternative contraception may be needed.
- St John’s wort can lower ritonavir levels and should be avoided.
- May interact with statins, blood thinners, seizure medicines, and tuberculosis treatments.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.