About risidiplam
Survival motor neuron 2 splicing modifier
Used for
- Treats spinal muscular atrophy in adults and children, including infants.
Usual adult dose
Usually 5 mg by mouth or feeding tube once daily for adults.
Usual dose in children
Once daily: 0.2 mg for infants under 2 months; 0.25 mg for ages 2 months to under 2 years; 0.25 mg for ages 2 years and older weighing under 20 kg; 5 mg if 2 years or older and 20 kg or more.
Common side effects
- Fever
- Diarrhea
- Rash
- Respiratory or urinary infections
Important warnings
- Avoid contact with skin or eyes; can harm an unborn baby.
- Use caution with medicines that may affect the retina.
- Do not take if allergic to risdiplam.
Pregnancy
May harm an unborn baby. Effective contraception is recommended during treatment and for one month after the last dose.
Breastfeeding
It is unknown whether risdiplam passes into breast milk; discuss potential infant risks with a healthcare professional.
Interactions
- Avoid medicines that may increase risdiplam exposure, such as metformin, unless monitored.
- Risdiplam may increase exposure to medicines transported by MATE proteins, including metformin.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.