About reteplase
Thrombolytic (fibrinolytic) agent
Used for
- Dissolves blood clots in adults with acute heart attacks (STEMI).
Usual adult dose
Adults: 10 units by intravenous injection, followed by another 10 units 30 minutes later.
Common side effects
- Bleeding, including serious internal bleeding
- Low blood pressure
- Allergic reactions
- Irregular heart rhythms
Important warnings
- Major bleeding can occur, including bleeding in the brain.
- Avoid use with active bleeding, recent stroke, or uncontrolled severe hypertension.
- Recent surgery, trauma, or other bleeding risks need careful assessment.
- Use with other clot-affecting medicines increases bleeding risk.
Pregnancy
Use only when clearly necessary; evidence is limited, and maternal bleeding risks require specialist assessment.
Breastfeeding
Information is limited; use requires a careful assessment of benefits and risks.
Interactions
- Anticoagulants, such as heparin or warfarin, increase bleeding risk.
- Antiplatelets, such as aspirin or clopidogrel, increase bleeding risk.
- Other thrombolytic medicines increase bleeding risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.