About recombina nt human tissue
Thrombolytic (tissue plasminogen activator)
Used for
- Dissolves clots in certain heart attacks, strokes, and pulmonary embolisms.
- Restores blood flow to blocked catheters.
Usual adult dose
Dose depends on the condition and body weight; given intravenously by trained clinicians using condition-specific protocols.
Common side effects
- Bleeding, including serious internal bleeding
- Brain haemorrhage
- Nausea or vomiting
- Allergic reactions
Important warnings
- Can cause life-threatening bleeding; avoid when bleeding risk is high.
- Not suitable for some recent surgeries, head injuries, strokes, or uncontrolled high blood pressure.
- Stroke treatment requires brain imaging and strict time limits.
- Use only in a hospital under specialist supervision.
Pregnancy
Use only when the expected benefit outweighs potential risks; pregnancy-specific evidence is limited.
Breastfeeding
Information is limited; clinical assessment is needed before use.
Interactions
- Anticoagulants and antiplatelet medicines increase bleeding risk.
- Other medicines affecting clotting can increase bleeding risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.