About recombina nt human coagulati
Recombinant factor VIII clotting factor
Used for
- Prevention and treatment of bleeding in haemophilia A
- Bleeding control during surgery in haemophilia A
Usual adult dose
Individualised by body weight, bleeding severity, and factor VIII levels; often 20–40 IU/kg per dose for routine prophylaxis.
Usual dose in children
Individualised by body weight and factor VIII levels; often 20–40 IU/kg per dose for routine prophylaxis.
Common side effects
- Headache
- Fever
- Injection-site reactions
- Development of factor VIII inhibitors
Important warnings
- Factor VIII inhibitors can reduce treatment effectiveness.
- Severe allergic reactions, including anaphylaxis, may occur.
- Dose and frequency depend on bleeding severity and measured factor levels.
- Not for treating von Willebrand disease.
Pregnancy
Limited human data; use only when clinically needed under specialist supervision.
Breastfeeding
Limited information; discuss use with a healthcare professional.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.