About rasburicase
Urate-lowering enzyme
Used for
- Prevents or treats high uric acid in adults and children receiving cancer treatment.
Usual adult dose
0.2 mg/kg by intravenous infusion once daily, usually for up to 5 days.
Usual dose in children
0.2 mg/kg by intravenous infusion once daily, usually for up to 5 days.
Common side effects
- Allergic reactions, including severe reactions
- Nausea or vomiting
- Fever
- Headache
Important warnings
- Can cause severe allergic reactions; infusion requires monitoring.
- Avoid in glucose-6-phosphate dehydrogenase deficiency due to risk of haemolysis and methemoglobinaemia.
- Blood samples require special handling to prevent falsely low uric acid results.
- Not for prevention or treatment of high uric acid from causes other than cancer therapy.
Pregnancy
Pregnancy data are limited; use only when clearly necessary after clinical assessment.
Breastfeeding
Breastfeeding is generally avoided during treatment because effects on the infant are unknown.
Interactions
- No major medicine interactions are well established; tell the treatment team about all medicines.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.