About ranitidine hydrochloride
Histamine-2 receptor blocker
Used for
- Previously used for heartburn, indigestion, and stomach or duodenal ulcers.
- Previously used for reflux and excess stomach acid.
Usual adult dose
Commonly 150 mg twice daily for ulcers or reflux; doses vary by condition and kidney function.
Usual dose in children
For children, dosing is weight-based and condition-specific; specialist guidance is required.
Common side effects
- Headache
- Diarrhea or constipation
- Nausea
- Rarely, confusion or abnormal heart rhythm
Important warnings
- Ranitidine products were withdrawn or suspended in many countries because of NDMA contamination concerns.
- Availability and regulatory status vary by country; check current local guidance.
- Dose reduction may be needed with kidney impairment.
- Seek urgent care for vomit containing blood or black stools.
Pregnancy
Historical data have not shown a clear increased risk, but use depends on local availability and clinician guidance.
Breastfeeding
Small amounts may enter breast milk; discuss suitability with a healthcare professional.
Interactions
- Warfarin: monitoring may be needed.
- Atazanavir and some other medicines need stomach acid for absorption.
- Antacids can affect absorption; separate doses as directed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.