About raltegravir
HIV integrase strand transfer inhibitor
Used for
- Treats HIV-1 infection with other HIV medicines.
Usual adult dose
Adults: 400 mg by mouth twice daily with other HIV medicines.
Usual dose in children
For children, dosing depends on age and weight; this 400 mg tablet is generally used for children weighing at least 25 kg.
Common side effects
- Nausea, headache, or dizziness
- Diarrhea or trouble sleeping
- Raised creatine kinase; rarely, muscle breakdown
- Rare severe allergic or skin reactions
Important warnings
- Can cause muscle pain or weakness; seek assessment for severe symptoms.
- Rarely causes serious allergic reactions or severe skin reactions.
- HIV medicines should not be stopped without clinical guidance.
- Does not prevent HIV transmission.
Pregnancy
Can be used during pregnancy when clinically indicated; treatment helps prevent HIV transmission to the baby.
Breastfeeding
People with HIV are generally advised not to breastfeed where safe alternatives are available, to prevent transmission.
Interactions
- Antacids containing aluminum or magnesium can reduce absorption; avoid taking together.
- Rifampin can lower raltegravir levels; dose adjustment may be needed.
- May interact with other medicines, including some anticonvulsants and supplements.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.