About rabeprazole sodium + sodium bicarbonate
Proton pump inhibitor plus antacid
Used for
- Short-term treatment of gastroesophageal reflux disease (GERD)
- Treatment of stomach or duodenal ulcers
- Reducing stomach acid in selected conditions
Usual adult dose
Combination doses vary by product and indication; use the labeled regimen. Rabeprazole alone is commonly taken once daily.
Common side effects
- Headache
- Diarrhea or abdominal discomfort
- Nausea
- Gas
Important warnings
- Long-term use may increase fracture, low magnesium, or vitamin B12 deficiency risks.
- Rarely, severe diarrhea or kidney inflammation can occur.
- Sodium bicarbonate adds sodium; caution with heart failure, kidney disease, or sodium restriction.
- Do not use for immediate relief of occasional heartburn.
Pregnancy
Human data are limited; use during pregnancy only when clinically needed and directed by a healthcare professional.
Breastfeeding
It is unclear whether both ingredients pass into breast milk; discuss use with a healthcare professional.
Interactions
- May reduce absorption of medicines requiring stomach acid, such as some antifungals.
- Rabeprazole can interact with warfarin, methotrexate, and rilpivirine.
- Sodium bicarbonate may affect absorption of medicines taken at the same time.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.