About rabeprazo le
Proton pump inhibitor
Used for
- Gastro-oesophageal reflux disease (GERD) and erosive reflux
- Duodenal ulcers
- Helicobacter pylori eradication with antibiotics
- Excess stomach acid from Zollinger–Ellison syndrome
Usual adult dose
Usually 20 mg once daily for reflux or ulcers; for H. pylori, 20 mg twice daily with antibiotics. Specialist dosing varies for Zollinger–Ellison syndrome.
Usual dose in children
For ages 12 and older with GERD, usually 20 mg once daily for up to 8 weeks. Not generally used below age 12.
Common side effects
- Headache
- Diarrhoea or constipation
- Abdominal pain or nausea
- Long-term use may lower magnesium or vitamin B12
Important warnings
- Seek urgent care for severe allergic reaction or persistent severe diarrhoea.
- Long-term use may increase fracture risk and rarely cause kidney inflammation.
- May mask symptoms of stomach cancer; evaluation may be needed for persistent symptoms.
- Swallow tablets whole; do not crush or chew.
Pregnancy
Limited safety information; use only when a clinician considers it necessary.
Breastfeeding
Unknown whether rabeprazole passes into breast milk; discuss use with a clinician.
Interactions
- May reduce absorption of medicines needing stomach acid, including some antifungals.
- Avoid with rilpivirine-containing medicines.
- May affect warfarin, methotrexate, digoxin, or ciclosporin; monitoring may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.