About rabbit anti human thymocyte immunoglobulin
Rabbit-derived immunosuppressive antibody
Used for
- Preventing rejection after kidney transplantation
- Treating acute kidney transplant rejection
- Treating aplastic anaemia in some settings
Usual adult dose
Kidney transplant rejection prevention: commonly 1.5 mg/kg intravenously daily for 4–7 days. Other uses vary.
Usual dose in children
For kidney transplant rejection prevention, commonly 1.5 mg/kg intravenously daily for 4–7 days; specialist dosing varies.
Common side effects
- Infusion reactions, fever, chills, and rash
- Low white blood cell or platelet counts
- Infections, including serious infections
- Serum sickness or allergic reactions
Important warnings
- Requires hospital administration and close monitoring during infusion.
- Can cause severe allergic reactions, including anaphylaxis.
- Increases infection risk and may reactivate latent infections.
- Dose may need adjustment for low blood counts.
Pregnancy
May harm a developing baby; pregnancy data are limited. Use requires specialist assessment.
Breastfeeding
It is not known whether this medicine passes into breast milk; breastfeeding decisions require specialist assessment.
Interactions
- Other immunosuppressants increase infection and blood-count risks.
- Live vaccines may be unsafe during treatment and for a period afterward.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.