About quetiapine
Second-generation antipsychotic
Used for
- Schizophrenia
- Bipolar disorder, including manic and depressive episodes
- Add-on treatment for major depressive disorder in adults
Usual adult dose
Usually 150–800 mg daily, depending on the condition and formulation; immediate-release doses are often divided.
Usual dose in children
For schizophrenia, ages 13–17: usually 400–800 mg daily. For bipolar mania, ages 10–17: usually 400–600 mg daily.
Common side effects
- Sleepiness, dizziness, and dry mouth
- Constipation and weight gain
- Increased blood sugar and cholesterol
- Fast heartbeat or low blood pressure on standing
Important warnings
- May increase risk of death in older adults with dementia-related psychosis.
- Can cause suicidal thoughts, especially in younger people or when treatment changes.
- May cause severe sleepiness, falls, high blood sugar, or movement problems.
- Do not stop suddenly without medical guidance.
Pregnancy
Use only after weighing benefits and risks; exposure near delivery may cause newborn withdrawal or movement symptoms.
Breastfeeding
May pass into breast milk; discuss risks and monitoring with a healthcare professional.
Interactions
- Strong CYP3A4 inhibitors, such as ketoconazole, can raise quetiapine levels.
- CYP3A4 inducers, such as carbamazepine, can lower its levels.
- Alcohol and sedating medicines can worsen drowsiness.
- Medicines that prolong QT interval can increase abnormal heart-rhythm risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.