About pyridostig mine bromide
Acetylcholinesterase inhibitor
Used for
- Treats myasthenia gravis
- Reverses effects of certain muscle-relaxing medicines after surgery
Usual adult dose
Myasthenia gravis: commonly 30–60 mg every 3–4 hours while awake; dose is individualized.
Usual dose in children
Myasthenia gravis: dosing is weight-based and individualized by a specialist.
Common side effects
- Diarrhea, nausea, or stomach cramps
- Increased saliva or sweating
- Muscle cramps or twitching
- Slow heartbeat
Important warnings
- May worsen breathing or muscle weakness if the dose is excessive.
- Use caution with asthma, slow heartbeat, or intestinal or urinary blockage.
- Seek urgent help for severe breathing difficulty, fainting, or marked weakness.
Pregnancy
Use only when needed and under medical supervision; untreated myasthenia gravis also carries risks.
Breastfeeding
Limited information is available; discuss use with a clinician, particularly for premature or newborn infants.
Interactions
- Other medicines that slow the heart may increase slow-heartbeat risk.
- Anticholinergic medicines, such as atropine, can oppose its effects.
- Some antibiotics, including aminoglycosides, may worsen myasthenia gravis.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.