About protein c
Plasma-derived protein C replacement
Used for
- Treats severe congenital protein C deficiency.
- Prevents and treats blood clots and purpura fulminans in severe deficiency.
Usual adult dose
Dose is individualized using body weight, protein C activity, and clinical response; given intravenously.
Usual dose in children
Individualized by body weight and protein C activity; given intravenously, including in newborns.
Common side effects
- Rash or itching
- Dizziness
- Fever
- Allergic reactions, including severe reactions
Important warnings
- Use under specialist supervision with protein C activity monitoring.
- May cause serious allergic reactions, especially in people with protein C allergy.
- Contains heparin; avoid in people with heparin-induced thrombocytopenia.
- Tell clinicians about other medicines that affect blood clotting.
Pregnancy
Use only when clearly needed; evidence is limited, and pregnancy increases clotting risk in protein C deficiency.
Breastfeeding
It is not known whether protein C enters breast milk; use requires clinical assessment.
Interactions
- Anticoagulants, including warfarin, can alter bleeding or clotting risk.
- Other medicines affecting coagulation may increase bleeding or clotting risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.