About progesterone
Natural progesterone hormone
Used for
- Supports the uterine lining during assisted reproduction.
- Treats secondary amenorrhea in selected patients.
Usual adult dose
Assisted reproduction: 90 mg vaginally once daily; some patients use twice daily. Secondary amenorrhea: 45 mg vaginally every other day, up to six doses.
Common side effects
- Vaginal discharge or irritation
- Headache
- Breast tenderness
- Abdominal discomfort or nausea
Important warnings
- Use only for the prescribed indication and duration.
- Seek urgent care for chest pain, breathing difficulty, or one-sided leg swelling.
- May cause dizziness or drowsiness; use caution with driving.
- Do not use with unexplained vaginal bleeding or certain hormone-sensitive cancers.
Pregnancy
Used to support pregnancy in assisted reproduction; use only under clinician supervision.
Breastfeeding
Use only after discussing with a clinician; progesterone can enter breast milk.
Interactions
- Vaginal antifungal medicines may alter progesterone absorption.
- Some liver enzyme-inducing medicines can lower progesterone levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.