About prog este rone
Progesterone hormone
Used for
- Supports the womb lining during fertility treatment.
- Prevents premature birth in some pregnancies with a short cervix.
- Treats progesterone deficiency in selected menstrual or fertility conditions.
- Used with oestrogen in hormone replacement therapy, depending on local approval.
Usual adult dose
Varies by reason and route. Common regimens include 200 mg vaginally at bedtime for fertility support, or 200 mg orally at bedtime for part of each cycle with hormone therapy.
Common side effects
- Sleepiness or dizziness, especially after oral doses
- Headache
- Breast tenderness
- Vaginal discharge or irritation with vaginal use
Important warnings
- Oral progesterone may impair alertness; avoid driving if affected.
- Seek medical assessment for unexplained vaginal bleeding or possible blood clots.
- Do not use with certain hormone-sensitive cancers or severe liver disease.
- Dose and route differ by indication; oral and vaginal use are not interchangeable.
Pregnancy
Vaginal progesterone is used for specific fertility and pregnancy indications under medical supervision. Oral use during pregnancy depends on the indication and local guidance.
Breastfeeding
Progesterone passes into breast milk in small amounts; use depends on clinical need and product guidance.
Interactions
- Some enzyme-inducing medicines, such as carbamazepine or rifampicin, may reduce progesterone levels.
- Ketoconazole and some other enzyme inhibitors may increase progesterone exposure.
- Other medicines causing drowsiness may worsen sleepiness from oral progesterone.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.