About pregabalin
Anticonvulsant; neuropathic pain medicine
Used for
- Nerve pain, including diabetic neuropathy and post-shingles pain
- Fibromyalgia
- Partial-onset seizures, alongside other seizure medicines
- Generalized anxiety disorder in some countries
Usual adult dose
Usually 150–600 mg daily in two or three divided doses; lower doses may be needed with kidney impairment.
Common side effects
- Dizziness and sleepiness
- Blurred vision
- Swelling of hands or feet
- Weight gain
Important warnings
- Can cause serious breathing problems, especially with opioids or other sedatives.
- May cause dependence or withdrawal; reduce gradually under medical supervision.
- Can increase suicidal thoughts or mood changes.
- Impaired kidney function requires dose adjustment.
Pregnancy
Use during pregnancy may be associated with birth defects; use only when benefits outweigh risks.
Breastfeeding
Pregabalin enters breast milk. Effects on nursing infants are uncertain; discuss risks and benefits with a clinician.
Interactions
- Opioids, alcohol, and sedatives can increase drowsiness and breathing problems.
- Thiazolidinedione diabetes medicines may increase swelling and weight gain.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.