About prednisolone
Corticosteroid (glucocorticoid)
Used for
- Treats severe allergies and asthma flare-ups
- Reduces inflammation in autoimmune and inflammatory conditions
- Treats some blood, skin, and joint disorders
Usual adult dose
Varies by condition; commonly 5–60 mg once daily, usually in the morning, for a short course.
Usual dose in children
Varies by condition and body size; commonly 1–2 mg/kg daily for short courses, with a maximum often 40–60 mg.
Common side effects
- Increased appetite, indigestion, or trouble sleeping
- Mood changes or restlessness
- Higher blood sugar or blood pressure
- Greater risk of infection
Important warnings
- Do not stop suddenly after prolonged treatment; the dose may need gradual reduction.
- Can mask or worsen infections; seek medical review for chickenpox or measles exposure.
- Long-term use can affect growth, bones, eyes, and adrenal function.
- Take with food; dosing and tapering depend on the condition and treatment duration.
Pregnancy
May be used when needed; prolonged or high-dose treatment requires careful assessment of benefits and risks.
Breastfeeding
Usually compatible at low doses; high doses may temporarily reduce milk supply. Ask about timing after larger doses.
Interactions
- NSAIDs such as ibuprofen may increase stomach-ulcer or bleeding risk.
- Warfarin and some other medicines may need monitoring or dose adjustment.
- Rifampicin, some seizure medicines, and some antifungals can alter prednisolone levels.
- Live vaccines may be unsafe during immunosuppressive treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.